Digital printing for short run packaging.
According to research by SmithersPira, the global market value of packaging and label order done by digital printing is worth about 4.8 billion dollars.
Although many print shop is still runing offset printing press. Cost is always a key factor. Recently the HP Indigo and Xeikon press claim that they could be more cost effective than flexo up to runs of some 7,000 linear metres, also they could manage to process cardboard thickness up to 24pt.
For small businesss much aware of their return of investment, trying to find a balance between order quantity and per unit price is a smart choice, for small quantity orders, digital priting avoid plate cost and set up fee, however offset is well known as rapidly printing so the per unit price would drop down drastically as quantity increases.3000 pieces would be a commonly seen quantity that you could conside as a separation line.
Keep in mind that always inquire your printing supplier regarding to what to choose for you project, you might find their recommendation helpful for working it out within your budget for best possible printing outcome, no matter it's offset or digital.